Respiratory Viruses from Breath Samples: Virologists from Frankfurt University established AveloMask Workflow with QIAsymphony, ELITe InGenius and RespiFinder 2SMART panel
- Mar 24
- 2 min read
March 24, 2026. Avelo is pleased to announce new research results presented at the Annual Meeting of the German Society for Virology (GfV). The study, conducted by the Institute of Medical Virology at Goethe University Frankfurt (Ciesek group), establishes a robust laboratory workflow for detecting respiratory viruses using the AveloMask Kit.
The research successfully integrated AveloMask breath samples into widely adopted diagnostic platforms, including QIAsymphony (Qiagen) and ELITe InGenius (ELITech) for extraction and RespiFinder 2SMART (Pathofinder) 24-plex PCR panel for detection.
In a first-of-its-kind proof of concept using human samples, researchers analyzed breath from symptomatic individuals and healthy controls. The workflow successfully detected key respiratory viruses, including SARS-CoV-2, influenza, and rhinovirus, from exhaled breath aerosols.
These findings highlight how non-invasive breath sampling can seamlessly integrate into existing clinical laboratory workflows, emphasizing AveloMask’s potential for future diagnostic and surveillance applications.
This work was conducted as part of the Horizon Europe project B-Path, a consortium dedicated to advancing non-invasive sampling for infectious disease diagnostics. Following these successful results, the B-Path project now aims to assess breath sampling in larger clinical studies.
View the study results presented at GfV 2026:
About Avelo
Avelo AG, the Swiss breath sampling company, aims to revolutionize the diagnosis of respiratory tract infections. Its breath collection device enables non-invasive collection of pathogens from breath aerosols and works with existing PCR tests. The novel device is designed for broad utility, similar to other sample collection technologies such as blood tubes.
About the Institute of Medical Virology, Goethe University Frankfurt
The Institute of Medical Virology at Goethe University Frankfurt is one of Germany’s leading centers for clinical and molecular virology. The institute, including the research group led by Prof. Sandra Ciesek, conducts research on emerging viruses, molecular diagnostics, and antiviral therapies, and is closely integrated with Frankfurt University Hospital and the German Centre for Infection Research (DZIF).
About B-Path
B-Path is a Horizon Europe consortium focused on developing novel technologies for detecting respiratory pathogens from exhaled breath. The project brings together academic, clinical, and industry partners across Europe to advance non-invasive sampling approaches for infectious disease diagnostics and surveillance.
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